A Rare Case of Persistent Mullerian Duct Syndrome

We report a rare case of Persistent Mullerain Duct Syndrome (PMDS) in a 16-year-old patient with bilateral undesceneded testes. On pathologic examination a uterus-like structure was seen which on histology showed endometrium and fallopian tube. Persistent Mullerian duct syndrome is a very rare form of male pseudo hermoaphroditism caused by lack of regression of Mullerian ducts in phenotypically and genotypically (46XY) male individuals. Mullerian duct derivatives include uterus, cervix, fallopian tubes and upper two-thirds of vagina. Mullerian ducts normally regress in male fetus at 8 weeks due to anti-Mullerian hormone (AMH), which binds to anti-Mullerian type 2 receptor causing disappearance of Mullerian ducts at 10 weeks of fetal age. Only about 200 cases have been described in literature so far.

Cytodiagnosis of Post-Traumatic Nodular Fasciitis

Reactive fibroblastic proliferations mimic sarcoma clinically and histologically. They need to be recognised and accurately diagnosed to differentiate from sarcomas and predict the prognosis. Nodular fasciitis (NF) is a benign myofibroblastic proliferation in the soft tissue. The most common locations are the upper extremities, followed by trunk, particularly the chest wall and back. We studied the aspirate obtained from a pre-auricular post-traumatic swelling in a boy, and a diagnosis of reactive fibroblastic proliferation was made after ruling out other common tumours in that region. Subsequent histology confirmed NF and helped in the management of the case.